Macrolides and analogues
Medchemexpress LLC Zearalenone-13C18 | 911392-43-3 | 98.7% | 336.23 g/mol | 13C18H22O5 | 30 UG
Zearalenone-13C18 is a fully 13C-labeled isotopic internal standard of the mycotoxin zearalenone, intended for use as an analytical reference in GC- and LC-MS quantification. The compound has CAS number 911392-43-3, molecular formula 13C18H22O5, and molecular weight 336.23 g/mol. It is supplied as a pre-weighed quantity for analytical laboratory use.
- Fully 13C-labeled internal standard for mass spectrometry.
- High purity (98.7%) to support accurate quantification.
- Suitable for GC- and LC-MS analytical methods.
- Supplied as a 30 μg pack for trace-level analyses.
Abcam Epothilone D, Microtubule-stabilizing agent, 5MG
MW 491.7 Da. Microtubule-stabilizing agent. Epothilone A (ab143615) and B (ab141271) analog. Improves microtubule density and axonal integrity Shows antineoplastic and neuroprotective effects in vivo. Blood-brain barrier permeable.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Epothilone B, Microtubule stabilizing agent, 100UG
MW 507.7 Da, Purity >98%. Microtubule-stabilizing agent. Analog of Epothilone A and D (ab143615 and ab143616). Displays highest efficacy in class III β-tubulin overexpressing malignancies. Inhibits Paclitaxel (ab120143)-resistant cell lines. Shows antitumor effects in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Apexbio Technology LLC Zearalenone(Synonyms: F-2 toxin, Mycotoxin F2, Zearalenolactone, RAL, ZEA, Zenon), 50mg, CAS: 17924-92-4.
Zearalenone (CAS 17924-92-4) is a mycotoxin produced primarily by Fusarium fungi frequently contaminating feed and food products It exhibits estrogenic activity through interaction with estrogen receptors thus altering endocrine signaling pathways Although acutely low in toxicity zearalenone effectively modulates estrogen receptor-mediated responses influencing hormonal balance in livestock species such as pigs cattle and sheep In biomedical research zearalenone serves as a tool compound to study estrogen receptor-mediated mechanisms and endocrine disruption particularly in young animals within veterinary pharmacological contexts
Apexbio Technology LLC (5Z)-7-Oxozeaenol(Synonyms: (5Z)-7-Oxozeaenol, 7-Oxozeaenol, TAK1 inhibitor, MAPKKK inhibitor), 5mg, CAS: 253863-19-3.
(5Z)-7-Oxozeaenol (CAS 253863-19-3) is a naturally occurring resorcylic lactone obtained from fungal sources It functions as a selective inhibitor of transforming growth factor -activated kinase 1 (TAK-1) a member of the mitogen-activated protein kinase kinase kinase (MAPKKK) family In biochemical assays (5Z)-7-Oxozeaenol inhibits purified TAK-1 with an IC50 of approximately 8 1 nM exhibiting minimal activity against related MAPKKKs Cellular studies indicate irreversible blockade of IL-1-stimulated TAK-1 NF- B and JNK/p38 signaling pathways This molecule is useful in inflammation research as demonstrated by its suppression of IL-1-induced COX-2 production and attenuation of inflammatory responses in mouse models
Medchemexpress LLC Epothilone F | 208518-52-9 | MFCD19982658 | 99.5% | 523.68 g/mol | C27H41NO7S | 5 MG
Epothilone F is a microtubule/tubulin-stabilizing research compound used in cellular and biochemical studies. It exhibits anti-tumor activity and inhibits proliferation in various cancer cell lines. Supplied at high reported purity and available in small milligram quantities for laboratory research.
- Microtubule/tubulin stabilizer used in cytoskeletal research.
- Demonstrated anti-tumor cellular activity in vitro.
- Supplied with reported purity of 99.45%.
- Available in small milligram package sizes suitable for assays.
- Provided in solid and solution formats for flexible use.
Sigma Aldrich Fine Chemicals Biosciences Zearalenone fungal mycotox10MG
ZEARALENONE5 Zearalenone fungal mycotox10MG
Abcam Epothilone B, Microtubule stabilizing agent, 10UG
MW 507.7 Da, Purity >98%. Microtubule-stabilizing agent. Analog of Epothilone A and D (ab143615 and ab143616). Displays highest efficacy in class III β-tubulin overexpressing malignancies. Inhibits Paclitaxel (ab120143)-resistant cell lines. Shows antitumor effects in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences Zearalenone fungal mycotox25MG
Zearalenone fungal mycotox25MG
Apexbio Technology LLC Epothilone D 189453-10-9 5mg
Epothilone D (189453-10-9) is a small-molecule microtubule-stabilizing agent It is designed to stabilize microtubules thereby disrupting essential cellular processes such as mitosis Epothilone D exerts its biological activity primarily through inhibition of microtubule depolymerization In in vitro assays Epothilone D demonstrates cytotoxic activity with IC50 values of 2 9 nM in MCF-7 cells 2 7 nM in KB-31 cells and 9 5 nM in CCRF-CEM cells Based on these pharmacological properties Epothilone D holds research potential in oncology and the study of drug resistance in cancer
Medchemexpress LLC Zearalenone (standard) | 17924-92-4 | MFCD00133085 | 98.9% | 318.36 g/mol | C18H22O5 | 25 MG
Zearalenone (standard) is an analytical reference standard of the mycotoxin zearalenone (CAS 17924-92-4) supplied as a solid for analytical and research use. It is intended for qualitative and quantitative method development and testing by HPLC, GC, and MS, and is supplied at high purity for reliable analytical performance.
- Analytical standard for HPLC, GC, and MS.
- High purity (≈98.9%) for reliable quantitation.
- Solid form for easy storage and handling.
- Suitable for qualitative and quantitative method development.
- Includes certificate of analysis for quality verification.